Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2350885 | 0.87 | MAPT (0.48) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7411536 | 0.84 | TDP1 (0.69) | HSD17B10HPGDALDH1A1KDM4EMAPK1 | |
| Benorilate SCHEMBL25167 | 0.83 | HSD17B10 (0.70) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| Benorilate SCHEMBL27446831 | 0.83 | HSD17B10 (0.70) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| Benorilate SCHEMBL15526470 | 0.83 | HSD17B10 (0.70) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL27533432 | 0.83 | MAPT (0.73) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7155169 | 0.83 | KDM4E (0.61) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| Benorilate SCHEMBL15969775 | 0.82 | HSD17B10 (0.68) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7085631 | 0.82 | HPGD (0.57) | HSD17B10HPGDMAPTALDH1A1KDM4E | |
| Acetic Acid SCHEMBL27603205 | 0.82 | MAPT (0.71) | HSD17B10HPGDMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| CN-102470120-A | Ophthalmic solutions for protecting the internal structure of the eyeball against ultraviolet rays or for treating keratoconus with a transepithelial cross-linking technique | SANSEVERINO RENATO | 2012-05-23 | — | — | CN | disclosed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | disclosed |
| US-6600063-B1 | Novel antimycobacterial compounds and in particular to antimycobacterial compounds comprised of derivatives of phenyl 4-aminosalicylate. This invention further relates to methods for their preparation, to form drugs | BOARD OF TRUSTEES OF WELLESLEY COLLEGE | 2003-07-29 | — | — | US | disclosed |
| WO-2002034203-A2 | NOVEL DERIVATIVES OF PHENYL 4-AMINOSALICYLATE AND METHOD OF MAKING THE SAME | WELLESLEY COLLEGE (US) | 2002-05-02 | — | — | WO | disclosed |
| EP-0100168-B1 | PROCESSES FOR PREPARING TABLETS BY A MODIFIED 'WET-GRANULATION' TECHNIQUE | Rogerson, Alan George (GB) | 1988-12-28 | — | — | EP | disclosed |
| EP-0100168-A2 | Processes for preparing tablets by a modified 'wet-granulation' technique | Rogerson, Alan George (GB) | 1984-02-08 | — | — | EP | disclosed |