Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | PDE4A | P27815 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | KDR | P35968 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533432 | 0.87 | MAPT (0.73) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| Acetic Acid SCHEMBL27603205 | 0.86 | MAPT (0.71) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| Phenyl Aminosalicylate SCHEMBL29711284 | 0.85 | MAPT (1.00) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| Phenyl Aminosalicylate SCHEMBL194250 | 0.85 | MAPT (1.00) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| SCHEMBL5314896 | 0.79 | SMN1; SMN2 (0.83) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| Acetaminosalol SCHEMBL5083330 | 0.79 | HPGD (0.94) | MAPTSMN1; SMN2LMNATP53HPGD | |
| Acetaminosalol SCHEMBL30383652 | 0.79 | HPGD (1.00) | MAPTSMN1; SMN2LMNATP53HPGD | |
| Acetaminosalol SCHEMBL25220 | 0.79 | HPGD (1.00) | MAPTSMN1; SMN2LMNATP53HPGD | |
| SCHEMBL20395085 | 0.78 | ALDH1A1 (0.71) | MAPTSMN1; SMN2LMNATP53CYP3A4 | |
| Acetaminosalol SCHEMBL579853 | 0.78 | HPGD (0.97) | MAPTSMN1; SMN2LMNATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109659-B1 | DISPERSANT COMBINATION FOR IMPROVED TRANSMISSION FLUIDS | LUBRIZOL CORP (US) | 2019-06-12 | — | — | EP | disclosed |
| US-7750089-B2 | Dispersant viscosity modifiers based on diene-containing polymers | THE LUBRIZOL CORPORATION (US) | 2010-07-06 | — | — | US | disclosed |
| WO-2010048137-A1 | REDUCING HIGH-AQUEOUS CONTENT SLUDGE IN DIESEL ENGINES | THE LUBRIZOL CORPORATION (US) | 2010-04-29 | — | — | WO | disclosed |
| US-20100099588-A1 | Dispersant Combination for Improved Transmission Fluids | THE LUBRIZOL CORPORATION | 2010-04-22 | — | — | US | disclosed |
| US-20070293409-A1 | Dispersant Viscosity Modifiers Based on Diene-Containing Polymers | THE LUBRIZOL CORPORATION (US) | 2007-12-20 | — | — | US | disclosed |
| EP-1730202-A2 | DISPERSANT VISCOSITY MODIFIERS BASED ON DIENE-CONTAINING POLYMERS | The Lubrizol Corporation (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005087821-A2 | DISPERSANT VISCOSITY MODIFIERS BASED ON DIENE-CONTAINING POLYMERS | THE LUBRIZOL CORPORATION (US) | 2005-09-22 | — | — | WO | disclosed |