SCHEMBL27533554

SCHEMBL27533554

CC(C#N)(Cc1ccccc1)OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
SGMS2 Q8NHU3 1/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
LMNA P02545 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAOB P27338 2/20 0.40
TSHR P16473 1/20 0.39
ATM Q13315 1/20 0.39
CYP1A1 P04798 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP1B1 Q16678 1/20 0.37
PTPN1 P18031 1/20 0.37
IDO1 P14902 1/20 0.36
TRPA1 O75762 1/20 0.36
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSK P43235 1/20 0.36
AGXT P21549 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686733 0.86 SGMS2 (0.41) SLC6A2TAAR1SGMS2LMNAMAOB
SCHEMBL27669066 0.81 SLC6A2 (0.45) SLC6A2TAAR1SGMS2ESR1ESR2
SCHEMBL10780111 0.79 SGMS2 (0.44) SLC6A2TAAR1SGMS2MAOBTSHR
SCHEMBL10775828 0.76 SGMS2 (0.42) SLC6A2TAAR1SGMS2MAOBTSHR
SCHEMBL31240845 0.76 MAOB (0.35) SGMS2MAOBTSHRATMIDO1
SCHEMBL15776936 0.75 SGMS2 (0.40) SGMS2MAOBTSHRCTSLCTSB
Phenol SCHEMBL28851094 0.73 LMNA (0.44) SLC6A2TAAR1ESR1ESR2LMNA
SCHEMBL11636438 0.72 TSHR (0.48) SLC6A2TAAR1LMNACYP2D6TSHR
SCHEMBL3410274 0.72 TSHR (0.48) SLC6A2TAAR1SGMS2LMNACYP2D6
Ammonia Solution, Strong SCHEMBL27480113 0.72 TSHR (0.48) SLC6A2TAAR1LMNACYP2D6MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1252018-C 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN claimed
CN-1252024-C 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN claimed
CN-1252017-C 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN claimed
CN-1562935-A 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN claimed
CN-1562929-A 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN claimed
CN-1562928-A 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN claimed
CN-1252024-C 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN disclosed
CN-1252018-C 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN disclosed
CN-1252017-C 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage UNIV WUHAN (CN) 2006-04-19 CN disclosed
CN-1252013-C (2)-3-[4-(1,1 dimethyl oxty1)-2-phenolic group] cyclohexanol, and synthetic method UNIV WUHAN (CN) 2006-04-19 CN disclosed
CN-1562935-A 3-[2-benzyloxy-4-(1,1-dimethyl octyl) phenyl] cycllhexanone, synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN disclosed
CN-1562925-A (2)-3-[4-(1,1 dimethyl oxty1)-2-phenolic group] cyclohexanol, and synthetic method UNIV WUHAN (CN) 2005-01-12 CN disclosed
CN-1562929-A 2-benzyloxy-1-bromine-4-(1,1-dimethyl octyl) benzene, synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN disclosed
CN-1562928-A 1-benzyloxy-3-(1.1 dimethyl-octane group) benzene as well as synthetic method and usage UNIV WUHAN (CN) 2005-01-12 CN disclosed