Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878679 | 0.83 | MAPT (0.48) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL431328 | 0.83 | MAPT (0.48) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL28879860 | 0.83 | MAPT (0.48) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL29954736 | 0.83 | MAPT (0.48) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL27594426 | 0.80 | MAPT (0.45) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL3136413 | 0.78 | KDM4E (0.56) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL5537149 | 0.77 | CYP19A1 (0.54) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL1282250 | 0.76 | MAPT (0.54) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL3817705 | 0.76 | MAPT (0.54) | MAPTKDM4ECYP19A1TBXAS1LOXL2 | |
| SCHEMBL6629717 | 0.76 | MAPT (0.54) | MAPTKDM4ECYP19A1TBXAS1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1296486-A | Glucocorticoid-selective anti-inflammatory agents | ABBOTT LAB (US) | 2001-05-23 | — | — | CN | claimed |