Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954736 | 1.00 | MAPT (0.48) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL3397178 | 0.87 | LOXL2 (0.58) | MAPTKDM4EERN1LMNAHTT | |
| SCHEMBL27536668 | 0.83 | MAPT (0.50) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL8534353 | 0.82 | CYP19A1 (0.50) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL28879860 | 0.81 | MAPT (0.48) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL431328 | 0.81 | MAPT (0.48) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL30045799 | 0.80 | CYP19A1 (0.48) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL27594426 | 0.79 | MAPT (0.45) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL3967767 | 0.79 | MAPT (0.54) | MAPTKDM4EPOLBCYP19A1TBXAS1 | |
| SCHEMBL763204 | 0.79 | MAPT (0.54) | MAPTKDM4EPOLBCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-105814040-B | The condensed 1,4- dihydro two of inhibitor as thermal excited transcryption factor 1 dislikes ene derivative | 癌症研究科技有限公司 | 2019-07-30 | — | — | CN | disclosed |
| WO-2018039442-A1 | TREATMENT OF CANCER WITH INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES, INC. (US) | 2018-03-01 | — | — | WO | disclosed |
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |