Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.46 |
| ▸ | THRA | P10827 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439014 | 0.81 | THRB (0.50) | THRBTHRA | |
| SCHEMBL11439018 | 0.79 | THRB (0.48) | THRBTHRAPOLB | |
| SCHEMBL6939130 | 0.79 | MAPT (0.47) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2477305 | 0.79 | KMT2A (0.45) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2483534 | 0.79 | KMT2A (0.45) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2482426 | 0.79 | KMT2A (0.45) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL27537994 | 0.78 | THRB (0.47) | THRBTHRAALOX5 | |
| SCHEMBL283401 | 0.78 | ESR1 (0.49) | LMNAMAPTPOLBGAAKMT2A | |
| SCHEMBL2482478 | 0.77 | KMT2A (0.43) | THRBLMNAMAPTPOLBGAA | |
| SCHEMBL2507209 | 0.76 | LMNA (0.51) | LMNAMAPTPOLBGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |