Styrene

Styrene

SCHEMBL27539728

C=C=C=C.C=CC#N.C=Cc1ccccc1.O=C1C=C(c2ccccc2)C(=O)N1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.31
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
SIRT3 Q9NTG7 1/20 0.31
SIRT5 Q9NXA8 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8170034 0.96 ALDH1A1 (0.39) ALDH1A1TSHRPOLBSIRT2SIRT1
Styrene SCHEMBL27894820 0.95 ALDH1A1 (0.38) ALDH1A1TSHRPOLBSIRT2SIRT1
Styrene SCHEMBL19511683 0.94 ALDH1A1 (0.37) ALDH1A1TSHRPOLBSIRT2SIRT1
Styrene SCHEMBL27894826 0.92 ALDH1A1 (0.36) ALDH1A1TSHRPOLBSIRT2SIRT1
Acrylonitrile SCHEMBL27745124 0.89 BACE1 (0.35) ALDH1A1POLBSIRT2SIRT1SIRT3
Styrene SCHEMBL2998387 0.88 ALDH1A1 (0.47) ALDH1A1TSHRPOLBSIRT2SIRT1
Styrene SCHEMBL27911990 0.86 ALDH1A1 (0.45) ALDH1A1TSHRPOLBSIRT2SIRT1
Styrene SCHEMBL28171289 0.86 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL28100183 0.79 BACE1 (0.41) ALDH1A1KDM4E
Butadiene SCHEMBL28109974 0.77 BACE1 (0.39) ALDH1A1POLBSIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1264912-C Rubber modified styrene resin compositions for extrusion formingf CHI MEI CORP (CN) 2006-07-19 CN disclosed
CN-1264910-C Flame-retardant styrene resin compositions CHI MEI CORP (CN) 2006-07-19 CN disclosed
CN-1264911-C Rubber modified styrene resin compositions CHI MEI CORP (CN) 2006-07-19 CN disclosed
CN-1239601-C Serial thermoplastic polystyrene resin compositions QIMEI IND CO LTD (CN) 2006-02-01 CN disclosed
CN-1594416-A Rubber modified styrene resin compositions for extrusion formingf CHI MEI CORP (CN) 2005-03-16 CN disclosed
CN-1594414-A Flame-retardant styrene resin compositions CHI MEI CORP (CN) 2005-03-16 CN disclosed
CN-1594415-A Rubber modified styrene resin compositions CHI MEI CORP (CN) 2005-03-16 CN disclosed
CN-1468899-A Serial thermoplastic polystyrene resin compositions 奇美实业股份有限公司 2004-01-21 CN disclosed