Styrene

Styrene

SCHEMBL27911990

C=Cc1ccccc1.N.O=C1C=C(c2ccccc2)C(=O)N1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TSHR P16473 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
SIRT3 Q9NTG7 1/20 0.36
SIRT5 Q9NXA8 1/20 0.36
POLB P06746 1/20 0.36
BACE1 P56817 2/20 0.35
LMNA P02545 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
METAP1 P53582 2/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
RAB9A P51151 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2998387 0.98 ALDH1A1 (0.47) ALDH1A1TSHRSIRT2SIRT1SIRT3
Styrene SCHEMBL27894820 0.92 ALDH1A1 (0.38) ALDH1A1TSHRSIRT2SIRT1SIRT3
Styrene SCHEMBL8170034 0.90 ALDH1A1 (0.39) ALDH1A1TSHRSIRT2SIRT1SIRT3
Styrene SCHEMBL27894826 0.89 ALDH1A1 (0.36) ALDH1A1TSHRSIRT2SIRT1SIRT3
Styrene SCHEMBL19511683 0.87 ALDH1A1 (0.37) ALDH1A1TSHRSIRT2SIRT1SIRT3
Butadiene SCHEMBL28109974 0.86 BACE1 (0.39) ALDH1A1SIRT2SIRT1SIRT3SIRT5
SCHEMBL9104697 0.86 ALDH1A1 (0.41) ALDH1A1TSHRSIRT2SIRT1SIRT3
Styrene SCHEMBL27539728 0.86 ALDH1A1 (0.36) ALDH1A1TSHRSIRT2SIRT1SIRT3
Ammonia Solution, Strong SCHEMBL27711207 0.86 BACE1 (0.45) ALDH1A1BACE1LMNAHSD17B10MAOA
SCHEMBL28074223 0.85 SIRT2 (0.37) ALDH1A1SIRT2SIRT1SIRT3SIRT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104744873-A Low/high-heat-resistant ABS resin and preparation method thereof Nanjing jinshan automobile engineering plastic co ltd 2015-07-01 CN claimed
CN-102977535-B Flame-retardant styrene resin composition and molded article obtained therefrom CHI MEI CORP. (CN) 2014-10-29 CN claimed
CN-115873152-A Polymer for improving thermal deformation temperature of ABS and preparation method thereof 嘉兴华雯化工股份有限公司 2023-03-31 CN disclosed
CN-104744873-A Low/high-heat-resistant ABS resin and preparation method thereof Nanjing jinshan automobile engineering plastic co ltd 2015-07-01 CN disclosed
CN-102977539-B Rubber modified styrene resin and molded article produced using the same CHI MEI CORP 2015-04-22 CN disclosed
CN-102977535-B Flame-retardant styrene resin composition and molded article obtained therefrom CHI MEI CORP. (CN) 2014-10-29 CN disclosed
CN-102977539-A Rubber modified styrene resin and molded article produced using the same CHIMEI CORP 2013-03-20 CN disclosed
CN-102977535-A Flame-retardant styrene resin composition and molded article obtained therefrom CHIMEI INNOLUX CORP CMI 2013-03-20 CN disclosed