Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30433192 | 1.00 | ATM (0.57) | ATMMAPTGAAHPGDPOLB | |
| SCHEMBL20524695 | 0.83 | MAPT (0.49) | ATMMAPTGAAHPGDPOLB | |
| SCHEMBL29083934 | 0.83 | NPC1 (0.61) | MAPTGAAHPGDPOLBKMT2A | |
| SCHEMBL29960870 | 0.83 | NPC1 (0.61) | MAPTGAAHPGDPOLBKMT2A | |
| SCHEMBL287220 | 0.81 | ALDH1A1 (0.56) | MAPTGAAHPGDPOLBMEN1 | |
| SCHEMBL561284 | 0.80 | HTT (0.64) | MAPTGAAHPGDPOLBMEN1 | |
| Methyl 3,5-Dinitrobenzoate SCHEMBL418416 | 0.80 | SMN1; SMN2 (0.60) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL11718691 | 0.80 | GAA (0.50) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL2885990 | 0.80 | MAPT (0.56) | ATMMAPTGAAHPGDPOLB | |
| SCHEMBL56951 | 0.80 | ATM (0.77) | ATMGAAPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177972-A | PARP1 inhibitors and uses thereof | 新特拉有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-1088702-C | Disubstituted bicyclic heterocycles, their production and use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2002-08-07 | — | — | CN | disclosed |
| CN-1248251-A | Disubstituted bicyclic heterocycles, their production and use as medicaments | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-03-22 | — | — | CN | disclosed |