Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864700 | 0.86 | MAPT (0.56) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL5864648 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL27436187 | 0.82 | PTGER4 (0.43) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL5555718 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL6317833 | 0.77 | NPSR1 (0.55) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL5865211 | 0.71 | ALOX15 (0.56) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL6030460 | 0.71 | EPHX1 (0.54) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL24489087 | 0.70 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL5192913 | 0.70 | NPSR1 (0.48) | ALDH1A1MAPTHPGDNPSR1KDM4E | |
| SCHEMBL5096639 | 0.69 | ALDH1A1 (0.73) | ALDH1A1MAPTHPGDNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1122037-C | Thieno [2, 3-d ] pyrimidinediones, preparation method and use thereof, and pharmaceutical compositions containing the same | ASTRA PHARMA PROD (GB) | 2003-09-24 | — | — | CN | disclosed |
| CN-1264382-A | Novel compounds | ASTRA PHARMA PROD (GB) | 2000-08-23 | — | — | CN | disclosed |