Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27960544 | 0.88 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL27796426 | 0.85 | LOXL2 (0.65) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL27775507 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL127411 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MEP1B | |
| SCHEMBL29471996 | 0.84 | SLC7A5 (0.62) | SLC7A5LOXL2CYP4F2CYP4A11MEP1B | |
| SCHEMBL27476536 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL224130 | 0.84 | ALDH1A1 (0.75) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL27960526 | 0.82 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL28528856 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10TDP1SLC7A5 | |
| SCHEMBL27571589 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TSHRHSD17B10TDP1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952297-A | Compound | 奥斯陆大学 | 2019-06-28 | — | — | CN | disclosed |
| CN-103052636-B | D 2antagonist and synthetic method thereof and using method | Altos Therapeutics, LLC (US) | 2016-03-09 | — | — | CN | disclosed |
| CN-103052636-A | D2 antagonists, methods of synthesis and methods of use | ALTOS THERAPEUTICS LLC | 2013-04-17 | — | — | CN | disclosed |
| CN-1261276-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2000-07-26 | — | — | CN | disclosed |