Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543699 | 0.81 | HRH3 (0.50) | ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7425000 | 0.79 | DRD4 (0.51) | MAPTALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL7430392 | 0.79 | CACNA1G (0.61) | MAPTALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL27543703 | 0.77 | DRD4 (0.55) | MAPTALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL4541993 | 0.70 | DRD4 (0.61) | MAPTDRD4LMNATSHRSMN1; SMN2 | |
| SCHEMBL27917206 | 0.69 | CYP4F2 (0.33) | — | |
| SCHEMBL27872635 | 0.68 | LMNA (0.32) | LMNA | |
| SCHEMBL27926970 | 0.68 | — | — | |
| SCHEMBL27545044 | 0.68 | — | — | |
| SCHEMBL11628082 | 0.67 | MAPT (0.51) | MAPTALDH1A1DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1278820-A | Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase | GLAXO GROUP LTD (GB) | 2001-01-03 | — | — | CN | disclosed |