SCHEMBL2754420

SCHEMBL2754420

c1ccc(-c2cc(-c3ccc(-c4ccc(N(c5ccccc5)c5cccc6ccccc56)cc4)cc3)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 8/20 0.46
▸ KMT2A Q03164 8/20 0.46
▸ ALDH1A1 P00352 7/20 0.46
▸ MAPT P10636 7/20 0.46
▸ HPGD P15428 7/20 0.46
▸ NTSR1 P30989 1/20 0.46
▸ KDM4E B2RXH2 5/20 0.44
▸ LMNA P02545 3/20 0.44
▸ GLA P06280 2/20 0.44
▸ ADORA2A P29274 1/20 0.41
▸ ADORA1 P30542 1/20 0.41
▸ CYP2C19 P33261 2/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ RXFP1 Q9HBX9 1/20 0.39
▸ MAOA P21397 2/20 0.38
▸ MAOB P27338 2/20 0.38
▸ ABCG2 Q9UNQ0 1/20 0.38
▸ DHODH Q02127 1/20 0.38
▸ PDE5A O76074 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754489 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL14079794 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754417 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754418 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL14079797 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754484 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754487 1.00 MEN1 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754502 0.99 MEN1 (0.47) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754432 0.99 MEN1 (0.47) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL2754490 0.99 MEN1 (0.47) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 — — US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 — — US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 — — US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 — — US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 — — US disclosed
US-20210135124-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-06 — — US disclosed
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-03-18 — — US disclosed
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-05-07 — — US disclosed
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2019-04-16 — — US disclosed
US-9960360-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 — — US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 — — US disclosed
US-20110315963-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-12-29 — — US disclosed
US-20110248247-A1 ORGANIC EL DISPLAY UNIT, METHOD OF MANUFACTURING THE SAME, AND SOLUTION USED IN METHOD SONY CORPORATION (JP) 2011-10-13 — — US disclosed
US-20110248247-A1 ORGANIC EL DISPLAY UNIT, METHOD OF MANUFACTURING THE SAME, AND SOLUTION USED IN METHOD SONY CORPORATION (JP) 2011-10-13 — — US disclosed
US-20110193476-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-08-11 — — US disclosed
US-20110193476-A1 ORGANIC EL DISPLAY AND METHOD OF MANUFACTURING THE SAME SONY CORPORATION (JP) 2011-08-11 — — US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 — — US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 — — US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 — — US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 MEN1 1681/4885KMT2A 462/4885ALDH1A1 1166/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 MEN1 3396/4885KMT2A 825/4885ALDH1A1 1038/4885
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPL21, RPS21, AOC2 MEN1 1681/4885KMT2A 462/4885ALDH1A1 1166/4885
US-10283717-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 MEN1 2762/4885KMT2A 2384/4885ALDH1A1 171/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 MEN1 2762/4885KMT2A 2384/4885ALDH1A1 171/4885
US-10263192-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 MEN1 2762/4885KMT2A 2384/4885ALDH1A1 171/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 MEN1 3396/4885KMT2A 825/4885ALDH1A1 1038/4885
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SCO2, NUDC MEN1 3241/4885KMT2A 3531/4885ALDH1A1 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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