Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132185 | 0.82 | HRH4 (0.35) | HRH4 | |
| SCHEMBL23152497 | 0.80 | HTR7 (0.46) | CYP17A1HTR7CHRM1HRH4 | |
| SCHEMBL2272239 | 0.80 | HTR3E (0.47) | CYP17A1HTR7PSEN1PSEN2APH1B | |
| SCHEMBL30790721 | 0.78 | CYP17A1 (0.44) | CYP17A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2563048 | 0.78 | USP30 (0.39) | — | |
| Hydrochloric Acid SCHEMBL2272152 | 0.78 | HTR3E (0.46) | CYP17A1HTR7PSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL16684961 | 0.78 | HTR3E (0.46) | CYP17A1HTR7PSEN1PSEN2APH1B | |
| SCHEMBL3895823 | 0.77 | CHKA (0.53) | — | |
| SCHEMBL16691310 | 0.77 | PSEN1 (0.47) | CYP17A1HTR7PSEN1PSEN2APH1B | |
| SCHEMBL24126771 | 0.77 | CHKA (0.52) | CYP17A1HTR7HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1311771-A | Benzamidine derivative | AJINOMOTO KK (JP) | 2001-09-05 | — | — | CN | claimed |
| CN-1311771-A | Benzamidine derivative | AJINOMOTO KK (JP) | 2001-09-05 | — | — | CN | disclosed |