Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 14/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884148 | 0.92 | HCAR2 (0.42) | HCAR2ALDH1A1MAPTTDP1ATM | |
| SCHEMBL1880535 | 0.92 | HCAR2 (0.42) | HCAR2ALDH1A1MAPTTDP1ATM | |
| SCHEMBL8641318 | 0.82 | HCAR2 (0.53) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8812196 | 0.82 | HCAR2 (0.53) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL29084608 | 0.80 | HCAR2 (0.57) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL27127631 | 0.80 | HCAR2 (0.57) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL8742013 | 0.80 | HCAR2 (0.57) | HCAR2ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL2021411 | 0.79 | HCAR2 (0.59) | HCAR2ALDH1A1ATMTSHRTP53 | |
| SCHEMBL7022068 | 0.79 | HCAR2 (0.59) | HCAR2ALDH1A1ATMTSHRTP53 | |
| SCHEMBL809870 | 0.79 | HCAR2 (0.59) | HCAR2ALDH1A1ATMTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100529798-C | Plastic lens material, plastic lens composition, plastic lens obtained by curing the composition and process for producing the plastic lens | SHOWA DENKO KK (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1281975-C | Composition for optical material, optical material and plastic lens | NOF CORP (JP) | 2006-10-25 | — | — | CN | disclosed |
| CN-1522374-A | Plastic lens material, plastic lens composition, plastic lens obtained by curing the composition, and method for producing the plastic lens | 昭和电工株式会社 | 2004-08-18 | — | — | CN | disclosed |
| CN-1461417-A | Composition for optical material, optical material and plastic lens | NOF CORP (JP) | 2003-12-10 | — | — | CN | disclosed |