SCHEMBL1884148

SCHEMBL1884148

COC(COC(=O)/C=C/C(=O)OCC(OC)OC)OC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42
ATM Q13315 1/20 0.41
TSHR P16473 2/20 0.40
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 3/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GFPT1 Q06210 1/20 0.32
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1880535 1.00 HCAR2 (0.42) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL27545596 0.92 HCAR2 (0.55) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL28632742 0.82 TSHR (0.63) TSHRALDH1A1HPGD
SCHEMBL2046400 0.79 TSHR (0.48) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL7086296 0.77 HCAR2 (0.48) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL7088994 0.77 HCAR2 (0.48) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL2349139 0.77 ALDH1A1 (0.41) TSHRTDP1ALDH1A1
SCHEMBL29084605 0.76 ATM (0.46) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL8742010 0.76 ATM (0.46) HCAR2KEAP1NFE2L2ATMTSHR
SCHEMBL317107 0.75 TSHR (0.67) HCAR2KEAP1NFE2L2ATMTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113165257-A Apparatus for producing cured resin film and method for producing cured resin film 昭和电工株式会社 2021-07-23 CN disclosed
US-7939612-B2 Radically polymerizable compound having a cyclic dithiocarbonate group SHOWA DENKO K.K. (JP) 2011-05-10 US disclosed
EP-1979383-B1 RADICALLY POLYMERIZABLE COMPOUND HAVING A CYCLIC DITHIOCARBONATE GROUP SHOWA DENKO KK (JP) 2010-09-22 EP disclosed
US-20100199491-A1 MANUFACTURING METHOD OF IMAGE PICK-UP DEVICE, IMAGE PICK-UP DEVICE AND OPTICAL ELEMENT KONICA MINOLTA OPTO, INC. (JP) 2010-08-12 US disclosed
EP-2166395-A1 IMAGING DEVICE MANUFACTURING METHOD, IMAGING DEVICE AND OPTICAL ELEMENT Konica Minolta Opto, Inc. (JP) 2010-03-24 EP disclosed
US-20090270574-A1 RADICALLY POLYMERIZABLE COMPOUND HAVING A CYCLIC DITHIOCARBONATE GROUP SHOWA DENKO K.K. (JP) 2009-10-29 US disclosed
EP-2094654-A1 RADICALLY POLYMERIZABLE COMPOUND HAVING A DITHIOCARBONATE STRUCTURE AND A SULFUR-CONTAINING ALLYLCARBONATE Showa Denko K.K. (JP) 2009-09-02 EP disclosed
EP-1791824-B1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO KK (JP) 2009-08-05 EP disclosed
US-20090192279-A1 Radically Polymerizable Sulfur-Containing Compound and Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2009-07-30 US disclosed
US-7518001-B2 Radically polymerizable sulfur-containing compound and radically polymerizable sulfur-containing polymer SHOWA DENKO K.K. (JP) 2009-04-14 US disclosed
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer SHOWA DENKO K.K. (JP) 2007-09-06 US disclosed
WO-2007086607-A2 RADICALLY POLYMERIZABLE COMPOUND HAVING A CYCLIC DITHIOCARBONATE GROUP SHOWA DENKO K.K. (JP) 2007-08-02 WO disclosed
EP-1791824-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER Showa Denko K.K. (JP) 2007-06-06 EP disclosed
WO-2006033438-A1 RADICALLY POLYMERIZABLE SULFUR-CONTAINING COMPOUND AND RADICALLY POLYMERIZABLE SULFUR-CONTAINING POLYMER SHOWA DENKO K.K. (JP) 2006-03-30 WO disclosed
US-6740721-B2 HAVING LOW VISCOSITY AND CAPABLE OF YIELDING A CURED MATERIAL HAVING A HIGH REFRACTIVE INDEX AND SMALL SPECIFIC GRAVITY SHOWA DENKO K.K. (JP) 2004-05-25 US disclosed
CN-1466598-A Plastic lens composition, plastic lens and method for producing the plastic lens �Ѻ͵繤��ʽ���� 2004-01-07 CN disclosed
US-20030149141-A1 Plastic lens composition, plastic lens,and process for producing the plastic lens SHOWA DENKO K.K. (JP) 2003-08-07 US disclosed
EP-1331494-A1 COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS NOF CORPORATION (JP) 2003-07-30 EP disclosed
EP-1328560-A2 PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS Showa Denko K.K. (JP) 2003-07-23 EP disclosed
WO-2002026843-A2 PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS SHOWA DENKO K. K. (JP) 2002-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270574-A1 RADICALLY POLYMERIZABLE COMPOUND HAVING A CYCLIC DITHIOCARBONATE GROUP RIF1, CCNT1, CCNA1 HCAR2 4630/4885KEAP1 223/4885NFE2L2 518/4885
US-20070208149-A1 Radically Polymerizable Sulfur-Containing Compound And Radically Polymerizable Sulfur-Containing Polymer CBS, TST, MSRB3 HCAR2 2982/4885KEAP1 340/4885NFE2L2 677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.