SCHEMBL8742013

SCHEMBL8742013

COCC(COC)COC(=O)C=CC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 14/20 0.57
ATM Q13315 1/20 0.41
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 4/20 0.36
TP53 P04637 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
EGLN3 Q9H6Z9 1/20 0.36
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084608 1.00 HCAR2 (0.57) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL27127631 1.00 HCAR2 (0.57) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL8742010 0.92 ATM (0.46) HCAR2ATMALDH1A1MAPTTDP1
SCHEMBL29084605 0.92 ATM (0.46) HCAR2ATMALDH1A1MAPTTDP1
SCHEMBL11745059 0.82 HCAR2 (0.63) HCAR2ATMTDP1TSHRTP53
SCHEMBL27545596 0.80 HCAR2 (0.55) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL403341 0.79 HCAR2 (0.67) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL403342 0.79 HCAR2 (0.67) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL2890671 0.79 HCAR2 (0.67) HCAR2ATMKDM4EALDH1A1MAPT
SCHEMBL7022068 0.79 HCAR2 (0.59) HCAR2ATMALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635577-A MIXTURES CONTAINING ORGANOSILICON COMPOUNDS OR POLYMERS SUBSTITUTED BY HYDROCARBON(PARTIALLY UNSATURATED) RADICALS, PLATINUM CATALYST, CATALYST INHIBITOR TO PREVENT ROOM TEMPERATURE REACTIONS AND A PERESTER INHIBITOR GENERAL ELECTRIC COMPANY (US) 1997-06-03 US claimed
US-5290885-A Hydrosilylation reaction DOW CORNING CORPORATION (US) 1994-03-01 US claimed
US-5248739-A Adhesive tapes DOW CORNING CORPORATION (US) 1993-09-28 US claimed
US-20260117089-A1 SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP DOW SILICONES CORP (US) 2026-04-30 US disclosed
US-20260117090-A1 SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP DOW SILICONES CORP (US) 2026-04-30 US disclosed
EP-4330340-B1 HYDROSILYLATION REACTION CURED SILICONE PRESSURE SENSITIVE ADHESIVE, COMPOSITION AND METHOD FOR ITS PREPARATION, AND USE IN FLEXIBLE DISPLAY DEVICE DOW SILICONES CORP (US) 2026-02-25 EP disclosed
US-12516229-B2 Printable silicone composition and methods for its preparation and use DOW SILICONES CORPORATION (US) 2026-01-06 US disclosed
EP-4642856-A1 CURABLE SILICONE COMPOSITION Dow Silicones Corporation (US) 2025-11-05 EP disclosed
US-12460114-B2 Hydrosilylation reaction cured silicone pressure sensitive adhesive, composition and method for its preparation, and use in a flexible display device DOW SILICONE CORPORATION (US) 2025-11-04 US disclosed
WO-2025226433-A1 SILICON RELEASE COATING WITH GREASE AND WATER BARRIER PROPERTIES DOW SILICONES CORPORATION (US) 2025-10-30 WO disclosed
EP-4298171-B1 SILICONE EMULSION AND METHODS FOR THE PREPARATION AND USE THEREOF DOW SILICONES CORP (US) 2025-01-29 EP disclosed
EP-2978795-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES Dow Corning Corporation (US) 2016-02-03 EP disclosed
WO-2014160975-A1 ORGANOSILOXANE COMPOSITIONS AND COATINGS, MANUFACTURED ARTICLES, METHODS AND USES DOW CORNING CORPORATION (US) 2014-10-02 WO disclosed
EP-0664328-B1 Moisture-curable silicone pressure sensitive adhesives DOW CORNING (US) 1997-10-08 EP disclosed
US-5658629-A BASE LAYER HAVING ONE SIDE IMPERVIOUS TO WATER VAPOR AND SILICONE MIGRATION AND SECOND SIDE PERMEABLE TO WATER VAPOR MORGAN ADHESIVES COMPANY (US) 1997-08-19 US disclosed
US-5545700-A OBTAINED BY THERMALLY CURING MIXTURE OF ENDCAPPED POLYSILICATE-POLYSILOXANE, ALKENYL-FUNCTIONAL POLYSILOXANE, POLYHYDROGENSILOXANE, ALKENETRIALKOXYSILANE, PLATINUM CONTAINING CATALYST, MOISTURE CURING CATALYST DOW CORNING CORPORATION (US) 1996-08-13 US disclosed
EP-0664328-A1 Moisture-curable silicone pressure sensitive adhesives DOW CORNING CORPORATION (US) 1995-07-26 EP disclosed
EP-0537784-B1 Silicone pressure sensitive adhesives having enhanced adhesion to low energy substrates DOW CORNING (US) 1995-03-01 EP disclosed
US-5248739-A Adhesive tapes DOW CORNING CORPORATION (US) 1993-09-28 US disclosed
EP-0537784-A1 Silicone pressure sensitive adhesives having enhanced adhesion to low energy substrates DOW CORNING CORPORATION (US) 1993-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117089-A1 SILICONE POLYETHER WITH LINEAR PENDANT POLYETHER GROUP SMC3, SGMS2, SMC2 HCAR2 3018/4885ATM 2302/4885KDM4E 1187/4885
US-20260117090-A1 SILICONE POLYETHER WITH BRANCHED PENDANT POLYETHER GROUP COG3, COG2, SMC3 HCAR2 2613/4885ATM 2226/4885KDM4E 1316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.