SCHEMBL27546196

SCHEMBL27546196

C=CCC(=O)O.C=COCCCCCCCCCCCCCCCCCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.41
HCAR2 Q8TDS4 2/20 0.41
GPR84 Q9NQS5 7/20 0.39
PPARG P37231 7/20 0.39
PPARD Q03181 7/20 0.39
PPARA Q07869 7/20 0.39
HDAC11 Q96DB2 5/20 0.39
PTPN1 P18031 3/20 0.39
ALDH1A1 P00352 2/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
FABP4 P15090 2/20 0.39
SLC22A6 Q4U2R8 1/20 0.39
SLC22A8 Q8TCC7 1/20 0.39
MEN1 O00255 1/20 0.39
ESR1 P03372 1/20 0.39
ALOX15 P16050 1/20 0.39
PDE4A P27815 1/20 0.39
KMT2A Q03164 1/20 0.39
PDE3A Q14432 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL253818 0.87 NAAA (0.47) TSHRHCAR2GPR84PPARGPPARD
Acetic Acid SCHEMBL4341301 0.85 TSHR (0.48) TSHRHCAR2GPR84PPARGPPARD
SCHEMBL11804110 0.85 TSHR (0.41) TSHRHCAR2ALDH1A1NAAACES2
Dodecanoate SCHEMBL29399839 0.84 GPR84 (0.61) TSHRGPR84PPARGPPARDPPARA
Acrylic Acid SCHEMBL27886045 0.84 HCAR2 (0.49) TSHRHCAR2GPR84ALDH1A1SLC22A6
Hexane SCHEMBL27744466 0.83 AKR1B1 (0.50) TSHRGPR84PPARGPPARDPPARA
Maleic Acid SCHEMBL11588241 0.82 HCAR2 (0.61) TSHRHCAR2ALDH1A1TDP1NAAA
Maleic Acid SCHEMBL11585463 0.82 HCAR2 (0.61) TSHRHCAR2ALDH1A1TDP1NAAA
SCHEMBL826318 0.81 TSHR (0.46) TSHRMEN1KMT2ANAAA
SCHEMBL292094 0.81 TSHR (0.46) TSHRMEN1KMT2ANAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101249047-B Use of polysiloxane/polyurea block copolymer for treatment of keratinous fibers OREAL 2013-10-23 CN disclosed
CN-1781476-B Cosmetic composition containing silicone elastomer bound to polyglycerol OREAL 2013-10-16 CN disclosed
CN-103328045-A Cosmetic composition for eyelashes OREAL 2013-09-25 CN disclosed
CN-101874766-B Wax-in-water emulsion including the combination of a glutamic acid derivative and an alkyl polyglycoside OREAL 2013-09-18 CN disclosed
CN-102970970-A Process for making up or caring for keratin fibres using retractable fibres, and use thereof OREAL 2013-03-13 CN disclosed
CN-101874766-A The water bag wax emulsion that contains the combination of glutamate derivatives and alkyl poly glucoside OREAL 2010-11-03 CN disclosed
CN-100586419-C Cosmetic composition comprising amorphous film-forming polymer and having certain thermal profile OREAL 2010-02-03 CN disclosed
CN-101249046-A Composition for dyeing keratinous fibres comprising a polysiloxane-polyurea block copolymer OREAL (FR) 2008-08-27 CN disclosed
CN-101249047-A Use of a polysiloxane/polyurea block copolymer for the treatment of keratinous fibers OREAL (FR) 2008-08-27 CN disclosed
CN-1259898-C Composition material containing adhesive wax for coating keratin fibre OREAL (FR) 2006-06-21 CN disclosed
CN-1781476-A Cosmetic composition containing silicone elastomer bound to polyglycerol OREAL (FR) 2006-06-07 CN disclosed
CN-1568923-A Cosmetic composition comprising at least one amorphous film-forming polymer and having a certain thermal profile OREAL (FR) 2005-01-26 CN disclosed
CN-1494892-A Composition material containing adhesive wax for coating keratin fibre �ź㴫 2004-05-12 CN disclosed
CN-1494887-A Face-beautifying compound containing adhesive wax �ź㴫 2004-05-12 CN disclosed