Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GRM8 | O00222 | 4/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.45 |
| ▸ | GRM6 | O15303 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743779 | 0.82 | L3MBTL1 (0.62) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL7110594 | 0.82 | L3MBTL1 (0.62) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL6745214 | 0.82 | L3MBTL1 (0.62) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL7733262 | 0.82 | AKR1C3 (0.53) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL27426836 | 0.80 | GSK3B (0.51) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL2081864 | 0.80 | AKR1C3 (0.67) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL2081866 | 0.80 | AKR1C3 (0.67) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL7723428 | 0.80 | ACP3 (0.48) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL7734348 | 0.79 | AKR1C3 (0.53) | L3MBTL1HTTSMN1; SMN2ACP3TSHR | |
| SCHEMBL4659329 | 0.79 | AKR1C3 (0.53) | L3MBTL1HTTSMN1; SMN2ACP3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101331125-A | N-(5-membered aromatic ring)-amido anti-viral compounds | GENELABS TECH INC (US) | 2008-12-24 | — | — | CN | disclosed |
| CN-100400041-C | Diaminothiazoles useful as selective inhibitors of CDK4 | HOFFMANN LA ROCHE (CH) | 2008-07-09 | — | — | CN | disclosed |
| CN-101146782-A | Meta-substituted thiazolidinone compounds, process for their preparation and their use as medicaments | BAYER SCHERING PHARMA AG (DE) | 2008-03-19 | — | — | CN | disclosed |
| CN-1324019-C | Azabicyclo salt compounds and their use to treat protein aging diseases | INST OF TOXIC MEDICINE ACADEMY (CN) | 2007-07-04 | — | — | CN | disclosed |
| CN-1652780-A | Diaminothiazoles used as CDK4 inhibitors | HOFFMANN LA ROCHE (CH) | 2005-08-10 | — | — | CN | disclosed |
| CN-1639146-A | Fused tricyclic heterocycles useful for the treatment of hyperproliferative diseases | BAYER PHARMACEUTICALS CORP (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1534028-A | New azabicyclo salt compounds and their use for treating protein aging diseases | 中国人民解放军军事医学科学院毒物药 | 2004-10-06 | — | — | CN | disclosed |