Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 3/20 | 0.47 |
| ▸ | GRM6 | O15303 | 3/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110594 | 1.00 | L3MBTL1 (0.62) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL6745214 | 1.00 | L3MBTL1 (0.62) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL2367944 | 0.88 | L3MBTL1 (0.64) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL1983563 | 0.88 | L3MBTL1 (0.64) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL9154689 | 0.86 | L3MBTL1 (0.62) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL2234292 | 0.86 | L3MBTL1 (0.62) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL31376571 | 0.86 | L3MBTL1 (0.62) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL23549441 | 0.85 | ALDH1A1 (0.65) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL7147271 | 0.85 | L3MBTL1 (0.61) | L3MBTL1MEN1HPGDKMT2ATSHR | |
| SCHEMBL6898173 | 0.85 | L3MBTL1 (0.65) | L3MBTL1MEN1HPGDKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6696573-B1 | SYNTHESIS OF SUCH AS 2-(N-(2-(9H-CARBAZOL-2-YLOXY)ETHYL))-AMINO-1-((3 -METHYLSULFONYLAMINO)PHENYL)ETHANOL WITH ENHANCED OPTICAL PURITY | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2004-02-24 | — | — | US | disclosed |
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2003-12-04 | — | — | US | disclosed |
| CN-1377342-A | Process for preparation of tricyclic amino alcohol derivatives | ASAHI CHEMICAL IND (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1209150-A1 | PROCESSES FOR THE PREPARATION OF TRICYCLIC AMINO ALCOHOL DERIVATIVES | Asahi Kasei Kabushiki Kaisha (JP) | 2002-05-29 | — | — | EP | disclosed |
| CN-1083831-C | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1295064-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 2001-05-16 | — | — | CN | disclosed |
| CN-1209119-A | Novel tricyclic compounds and pharmaceutical compositions containing them | ASAHI CHEMICAL IND (JP) | 1999-02-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225289-A1 | Process for the preparation of tricyclic amino alcohol derivatives | ADH1A, ADH1C, OXER1 | L3MBTL1 1385/4885MEN1 3399/4885HPGD 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.