Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 20/20 | 1.00 |
| ▸ | MMP13 | P45452 | 20/20 | 1.00 |
| ▸ | ADAM17 | P78536 | 19/20 | 1.00 |
| ▸ | MMP9 | P14780 | 19/20 | 1.00 |
| ▸ | MMP3 | P08254 | 1/20 | 0.62 |
| ▸ | MMP7 | P09237 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657799 | 0.90 | MMP1 (0.82) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL27547254 | 0.90 | MMP1 (0.85) | MMP1MMP13ADAM17MMP9MMP3 | |
| SCHEMBL6614299 | 0.89 | MMP1 (0.80) | MMP1MMP13ADAM17MMP9 | |
| Dimethylamine SCHEMBL7424112 | 0.88 | MMP1 (0.79) | MMP1MMP13ADAM17MMP9 | |
| Dimethylamine SCHEMBL6642543 | 0.88 | MMP1 (0.79) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL27537608 | 0.87 | MMP1 (0.84) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL27521569 | 0.87 | MMP1 (0.82) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL27547261 | 0.86 | MMP1 (0.75) | MMP1MMP13ADAM17MMP9MMP3 | |
| SCHEMBL3939993 | 0.86 | MMP13 (1.00) | MMP1MMP13ADAM17MMP9 | |
| SCHEMBL27547259 | 0.86 | MMP1 (0.79) | MMP1MMP13ADAM17MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1293663-A | 2,3,4,5-tetrahydro-1H-[1,4] benzodiazepine-3-hydroxamix acids as matrix metal-protease | AMERICAN CYANAMID CO (US) | 2001-05-02 | — | — | CN | claimed |