⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12248384 | 0.93 | — | — | |
| SCHEMBL13501654 | 0.84 | — | — | |
| SCHEMBL9290144 | 0.81 | — | — | |
| SCHEMBL13985052 | 0.78 | MEN1 (0.40) | — | |
| SCHEMBL15355632 | 0.77 | — | — | |
| SCHEMBL14342238 | 0.76 | INMT (0.41) | — | |
| SCHEMBL14477695 | 0.75 | PIK3CD (0.59) | — | |
| SCHEMBL22214536 | 0.74 | INMT (0.33) | — | |
| SCHEMBL22245293 | 0.74 | INMT (0.30) | — | |
| SCHEMBL7861266 | 0.74 | ALOX5 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020156494-A1 | CAPSID PROTEIN ASSEMBLY INHIBITOR CONTAINING PYRROLO HETEROCYCLE | 正大天晴药业集团股份有限公司 | 2020-08-06 | — | — | WO | disclosed |
| EP-2399667-B1 | Process for producing microcapsules | COGNIS IP MAN GMBH (DE) | 2017-03-08 | — | — | EP | disclosed |
| WO-2017017609-A1 | BETUIN DERIVATIVES FOR PREVENTING OR TREATING HIV INFECTIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-02-02 | — | — | WO | disclosed |
| EP-3124561-A1 | ACTIVE ENERGY RAY-CURABLE INKJET INK | Toyo Ink SC Holdings Co., Ltd. (JP) | 2017-02-01 | — | — | EP | disclosed |
| WO-2013003586-A1 | QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |
| US-8088771-B2 | Cycloalkylidene and heterocycloalkylidene inhibitor compounds | GILEAD SCIENCES, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-2225940-A1 | Oil dispersions of nAChR binding neonicotinoids | GAT Microencapsulation AG (AT) | 2010-09-08 | — | — | EP | disclosed |
| US-7723509-B2 | Conjugated lipophilic group with a modified nucleotide is used to target disease gene, cells, tissue, for drug delivery to target tumor cells; ribose sugar of nucleotide is replaced with a cyclic carrier which has at least one attached phosphate or phosphorothioate group; biodrugs | ALNYLAM PHARMACEUTICALS (US) | 2010-05-25 | — | — | US | disclosed |
| US-20100022543-A1 | CYCLOALKYLIDENE AND HETEROCYCLOALKYLIDENE INHIBITOR COMPOUNDS | GILEAD SCIENCES, INC. | 2010-01-28 | — | — | US | disclosed |
| US-20070161591-A1 | Methods and compositions for treating neurological disease | UNIVERSITY OF MASSACHUSETTS (US) | 2007-07-12 | — | — | US | disclosed |