Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27260088 | 0.83 | MAPK1 (0.47) | CYP1A2GAAMAPTRECQLKMT2A | |
| SCHEMBL27678742 | 0.82 | PLAU (0.45) | RECQLKMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL28742891 | 0.80 | ALOX5 (0.47) | — | |
| SCHEMBL19748762 | 0.78 | CYP1A2 (0.50) | HSD17B10CYP1A2GAAMAPTRECQL | |
| SCHEMBL9304892 | 0.78 | CYP1A2 (0.53) | HSD17B10CYP1A2GAAMAPTRECQL | |
| SCHEMBL27400964 | 0.75 | KMT2A (0.47) | HSD17B10CYP1A2GAAMAPTRECQL | |
| SCHEMBL28537560 | 0.74 | KMT2A (0.59) | HSD17B10CYP1A2GAAMAPTRECQL | |
| SCHEMBL27552377 | 0.73 | KDM4E (0.50) | HSD17B10CYP1A2GAAMAPTRECQL | |
| SCHEMBL5171388 | 0.72 | KMT2A (0.73) | CYP1A2GAAMAPTRECQLKMT2A | |
| SCHEMBL15134857 | 0.71 | KMT2A (0.51) | HSD17B10CYP1A2GAAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1291979-C | Imidazole compounds and their use as adenosine deaminase inhibitors | JUJISAWA PHARAMCEUTICAL CO LTD (JP) | 2006-12-27 | — | — | CN | disclosed |
| CN-1319095-A | Imidazole compounds and their use as adenosine deaminase inhibitors | JUJISAWA PHARAMCEUTICAL CO LTD (JP) | 2001-10-24 | — | — | CN | disclosed |