Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27678742 | 0.82 | PLAU (0.45) | — | |
| SCHEMBL27547745 | 0.80 | HSD17B10 (0.48) | — | |
| SCHEMBL27260088 | 0.79 | MAPK1 (0.47) | — | |
| SCHEMBL16124574 | 0.77 | ALOX5 (0.48) | ALOX5ACHECYP2D6PPARGPPARA | |
| SCHEMBL14783795 | 0.77 | MEN1 (0.61) | ALOX5ACHEPPARGPPARA | |
| SCHEMBL16124570 | 0.76 | ALOX5 (0.52) | ALOX5ACHEPPARGPPARA | |
| SCHEMBL21225979 | 0.72 | ALOX5 (0.57) | ALOX5ACHEPPARGPPARA | |
| SCHEMBL28044165 | 0.72 | PPARA (0.54) | PPARGPPARA | |
| SCHEMBL12881236 | 0.72 | ALOX5 (0.49) | ALOX5ACHEPPARGPPARA | |
| SCHEMBL28425617 | 0.72 | ALOX5 (0.53) | ALOX5ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282325-A | Arylthiazolidinedione derivatives | MERCK & CO INC (US) | 2001-01-31 | — | — | CN | disclosed |