Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.67 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylphenylether SCHEMBL61660 | 0.87 | LMNA (0.74) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| SCHEMBL13719578 | 0.85 | NR4A1 (0.64) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| SCHEMBL3054083 | 0.85 | PLA2G4B (0.64) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| SCHEMBL228290 | 0.85 | NR4A2 (0.74) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL10872821 | 0.85 | LMNA (0.72) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL28285060 | 0.85 | LMNA (0.65) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL23235842 | 0.84 | LMNA (0.71) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL8019776 | 0.84 | LMNA (0.71) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL9283359 | 0.84 | LMNA (0.71) | NR4A2NR4A1NR4A3LMNACYP1A2 | |
| Benzylphenylether SCHEMBL9549322 | 0.84 | LMNA (0.71) | NR4A2NR4A1NR4A3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1146542-C | Benzamide derivatives and their use as cytokine inhibitors | — | 2004-04-21 | — | — | CN | disclosed |
| CN-1319092-A | Benzamide derivatives and their use as cytokine inhibitors | ASTRAZENECA AB (SE) | 2001-10-24 | — | — | CN | disclosed |