Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.64 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.64 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115002 | 0.85 | PPARG (0.71) | PLA2G4BNR4A1NR4A2NR4A3LMNA | |
| Benzylphenylether SCHEMBL27549280 | 0.85 | NR4A2 (0.67) | PLA2G4BNR4A1NR4A2NR4A3LMNA | |
| SCHEMBL6013 | 0.85 | ALOX15 (0.68) | LMNAFFAR1MAPTMEN1KMT2A | |
| SCHEMBL7664334 | 0.84 | ADAMTS5 (0.52) | PLA2G4BNR4A1NR4A2NR4A3CYP1A2 | |
| SCHEMBL224149 | 0.84 | ALOX5 (0.65) | NR4A1NR4A2NR4A3LMNACYP1A2 | |
| Fluoride SCHEMBL27943650 | 0.83 | ALOX15 (0.65) | LMNAFFAR1MAPTMEN1KMT2A | |
| SCHEMBL2117441 | 0.82 | ALOX15 (0.50) | FFAR1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL228290 | 0.82 | NR4A2 (0.74) | PLA2G4BNR4A1NR4A2NR4A3LMNA | |
| SCHEMBL4432728 | 0.82 | PARP10 (0.70) | PLA2G4BNR4A1NR4A2NR4A3LMNA | |
| SCHEMBL20425306 | 0.82 | MAOB (0.70) | PLA2G4BNR4A1NR4A2NR4A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7186414-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1676832-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-6991798-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1102742-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2001-05-30 | — | — | EP | disclosed |
| WO-2000007979-A2 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | PLA2G4B 635/4885NR4A1 3390/4885NR4A2 3277/4885 |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | PLA2G4B 635/4885NR4A1 3390/4885NR4A2 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.