Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415603 | 0.84 | PPARA (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5415596 | 0.84 | PPARA (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1579754 | 0.80 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18572548 | 0.78 | MAOB (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5367466 | 0.77 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL11547077 | 0.76 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11547074 | 0.76 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19717163 | 0.76 | HDAC8 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17002904 | 0.76 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17002902 | 0.76 | CA12 (0.54) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1275940-C | New phenylalkyloxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2006-09-20 | — | — | CN | disclosed |
| CN-1535261-A | New phenylalkyloxy-phenyl derivatives | — | 2004-10-06 | — | — | CN | disclosed |