Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.49 |
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | PPARD | Q03181 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415603 | 1.00 | PPARA (0.49) | PPARAPPARGPPARDBCHEACHE | |
| SCHEMBL27549475 | 0.84 | CA12 (0.46) | PPARAPPARGPPARDBCHEACHE | |
| SCHEMBL5367466 | 0.82 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL14989357 | 0.81 | THRB (0.50) | PPARAPPARGPPARDBCHEACHE | |
| SCHEMBL14539076 | 0.80 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL27549472 | 0.80 | PPARA (0.45) | PPARAPPARGPPARD | |
| SCHEMBL2554435 | 0.79 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL3541115 | 0.79 | MMP8 (0.56) | PPARAPPARGPPARD | |
| SCHEMBL27546630 | 0.79 | MMP8 (0.56) | PPARAPPARGPPARD | |
| SCHEMBL3965096 | 0.78 | PPARA (0.50) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241923-B2 | Phenylalkyloxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2007-07-10 | — | — | US | disclosed |
| US-20040176444-A1 | Phenylalkyloxy-phenyl derivatives | ASTRAZENECA AB (SE) | 2004-09-09 | — | — | US | disclosed |
| EP-1404649-A1 | NEW PHENYLALKYLOXY-PHENYL DERIVATIVES | AstraZeneca AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096863-A1 | NEW PHENYLALKYLOXY-PHENYL DERIVATIVES | ASTRAZENECA AB (SE) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176444-A1 | Phenylalkyloxy-phenyl derivatives | GPR119, IAPP, INSR | PPARA 87/4885PPARG 53/4885PPARD 65/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.