SCHEMBL5367466

SCHEMBL5367466

C=Cc1ccc(C[C@H](OCC)C(=O)OCC)cc1

nearest known ligand 0.49

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 20/20 0.49
▸ PPARG P37231 13/20 0.46
▸ PPARD Q03181 11/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5689806 0.87 PPARA (0.65) PPARAPPARGPPARD
SCHEMBL9614800 0.83 MMP8 (0.50) —
SCHEMBL2554435 0.83 PPARA (0.52) PPARAPPARGPPARD
SCHEMBL5415603 0.82 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL5415596 0.82 PPARA (0.49) PPARAPPARGPPARD
SCHEMBL977513 0.81 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL977514 0.81 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL6419166 0.81 PPARA (0.54) PPARAPPARGPPARD
SCHEMBL3965096 0.81 PPARA (0.50) PPARAPPARGPPARD
SCHEMBL31731607 0.81 PPARA (0.51) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309720-B2 2-ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders ASTRAZENECA AB (SE) 2007-12-18 — — US disclosed
US-20060178432-A1 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders ASTRAZENECA AB (SE) 2006-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060178432-A1 2-Ethoxy-3-phenylpropionic acid derivatives for the treatment of lipid disorders LIPC, PNLIP, CPT1A PPARA 34/4885PPARG 72/4885PPARD 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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