SCHEMBL2755010

SCHEMBL2755010

CC(C)N1CCS/C1=N\C#N

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
CHRNA7 P36544 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PDE4B Q07343 17/20 0.37
PDE4D Q08499 8/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9007399 0.82 PDE4B (0.38) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL9007406 0.82 PDE4B (0.38) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL11033145 0.76
SCHEMBL3222391 0.76
SCHEMBL11033144 0.76
SCHEMBL13472021 0.75 INMT (0.30)
SCHEMBL24044988 0.72
SCHEMBL17604958 0.72 MEN1 (0.39) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL17604960 0.72 MEN1 (0.39) MEN1CHRNA7KMT2ATDP1PDE4B
SCHEMBL17686523 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293733-B2 Oil dispersions of nAChR binding neonicotinoids GAT MICROENCAPSULATION AG (AT) 2012-10-23 US disclosed
US-20120004104-A1 OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS GAT MICROENCAPSULATION AG (AT) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004104-A1 OIL DISPERSIONS OF nAChR BINDING NEONICOTINOIDS CHRND, ITGAM, CHRM2 MEN1 4692/4885CHRNA7 16/4885KMT2A 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.