Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859153 | 0.84 | SLC7A5 (0.35) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL27893717 | 0.84 | SLC7A5 (0.35) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL4934742 | 0.82 | SLC7A5 (0.42) | SLC7A5KMT2AMEN1NOS1NOS3 | |
| SCHEMBL4936597 | 0.82 | SLC1A2 (0.37) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL4936742 | 0.82 | SLC1A2 (0.37) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL4936722 | 0.82 | SLC7A5 (0.42) | SLC7A5KMT2AMEN1NOS1NOS3 | |
| SCHEMBL7814662 | 0.80 | NOS1 (0.37) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL31733944 | 0.80 | NOS1 (0.37) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL4106257 | 0.80 | KMT2A (0.39) | SLC7A5KMT2AMEN1GAANOS1 | |
| SCHEMBL27656864 | 0.80 | KMT2A (0.39) | SLC7A5KMT2AMEN1GAANOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1703395-A | Aryl and heteroaryl compounds and methods of modulating blood coagulation | TRANSTECH PHARMA INC (US) | 2005-11-30 | — | — | CN | disclosed |
| CN-1290248-A | Serine carbonates | GIVAUDAN ROURE INT (CH) | 2001-04-04 | — | — | CN | disclosed |