Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936597 | 1.00 | SLC1A2 (0.37) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| SCHEMBL3229578 | 0.89 | GRIK1 (0.45) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| SCHEMBL4935760 | 0.89 | GRIK1 (0.45) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| SCHEMBL4935592 | 0.87 | GRIK1 (0.46) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 | |
| SCHEMBL27550574 | 0.82 | SLC7A5 (0.36) | SLC1A1MEN1GAAKMT2ANOS1 | |
| SCHEMBL27893717 | 0.81 | SLC7A5 (0.35) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL27859153 | 0.81 | SLC7A5 (0.35) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL4934742 | 0.79 | SLC7A5 (0.42) | SLC1A2SLC1A3TDP1CTSKCTSS | |
| SCHEMBL4936722 | 0.79 | SLC7A5 (0.42) | SLC1A2SLC1A3TDP1CTSKCTSS | |
| SCHEMBL7076350 | 0.79 | CHRM1 (0.50) | SLC1A2SLC1A1GRIK1GRIK2SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080312080-A1 | Novel dioctatin derivatives and production process thereof | AKR7A2, HDHD5, DECR1 | SLC1A2 3634/4885SLC1A1 4159/4885GRIK1 3638/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.