Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024894 | 0.82 | ALDH1A1 (0.76) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL5028870 | 0.81 | ALDH1A1 (0.74) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL5024742 | 0.79 | L3MBTL1 (1.00) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL5013030 | 0.79 | ALDH1A1 (0.71) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL27570315 | 0.77 | CYP3A4 (0.62) | L3MBTL1ALDH1A1CYP2D6CYP2C19DPP7 | |
| SCHEMBL31232857 | 0.76 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL31232707 | 0.76 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 | |
| SCHEMBL6398876 | 0.76 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL27570311 | 0.75 | KDM4E (0.40) | ALDH1A1KDM4EPOLBDPP7SIGMAR1 | |
| SCHEMBL15995479 | 0.74 | ALDH1A1 (0.64) | L3MBTL1ALDH1A1ALOX15TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1344266-A | Novel compounds | ASTRAZENECA AB (SE) | 2002-04-10 | — | — | CN | claimed |
| CN-1344266-A | Novel compounds | ASTRAZENECA AB (SE) | 2002-04-10 | — | — | CN | disclosed |