Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GLI1 | P08151 | 1/20 | 0.44 |
| ▸ | GLI2 | P10070 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11339783 | 1.00 | DRD1 (0.65) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| SCHEMBL7703673 | 0.88 | DRD1 (0.52) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| SCHEMBL7515021 | 0.85 | CA2 (0.72) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| SCHEMBL11559990 | 0.82 | MAPT (0.62) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| SCHEMBL11334981 | 0.82 | HSD17B10 (0.55) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| SCHEMBL11334985 | 0.82 | HSD17B10 (0.55) | DRD1MAPTHSD17B10HIF1AKDM4E | |
| Docarpamine SCHEMBL219671 | 0.79 | DRD1 (1.00) | DRD1LMNACA2CA1TRPV1 | |
| Docarpamine SCHEMBL29831844 | 0.79 | DRD1 (1.00) | DRD1LMNACA2CA1TRPV1 | |
| Docarpamine SCHEMBL8923875 | 0.79 | DRD1 (1.00) | DRD1LMNACA2CA1TRPV1 | |
| SCHEMBL11459817 | 0.79 | MAPT (0.68) | DRD1MAPTHSD17B10HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1271049-C | Method for synthesizing polycarbo amide | SHANGHAI MEDICINES INST CHINES (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-1470506-A | Method for synthesizing polycarbo amide | 中国科学院上海药物研究所 | 2004-01-28 | — | — | CN | claimed |
| CN-1271049-C | Method for synthesizing polycarbo amide | SHANGHAI MEDICINES INST CHINES (CN) | 2006-08-23 | — | — | CN | disclosed |
| CN-1470506-A | Method for synthesizing polycarbo amide | 中国科学院上海药物研究所 | 2004-01-28 | — | — | CN | disclosed |