Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.47 |
| ▸ | GLI2 | P10070 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11334981 | 1.00 | HSD17B10 (0.55) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL3927180 | 0.82 | HDAC8 (0.57) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL3927183 | 0.82 | HDAC8 (0.57) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL27550844 | 0.82 | DRD1 (0.65) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL11339783 | 0.82 | DRD1 (0.65) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL7313613 | 0.82 | CTSC (0.62) | CTSCKCNH2KMT2ACA1CYP2D6 | |
| SCHEMBL24277516 | 0.81 | HDAC8 (0.61) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL29520758 | 0.81 | HDAC8 (0.61) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL15399610 | 0.81 | HDAC8 (0.61) | HSD17B10MAPTHIF1AKDM4ELMNA | |
| SCHEMBL24277517 | 0.81 | HDAC8 (0.61) | HSD17B10MAPTHIF1AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007441-B1 | N - (N-ACETYL-L-METHIONYL) - 3,4 -DIETHOXY-CARBONYLOXY-PHENETHYLAMINE, PROCESS FOR PREPARING SAME AND A PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND. | Tanabe Seiyaku Co., Ltd. (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4228183-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
| EP-0007441-A1 | N - (N-Acetyl-L-methionyl) - 3,4 -diethoxy-carbonyloxy-phenethylamine, process for preparing same and a pharmaceutical composition containing said compound. | Tanabe Seiyaku Co., Ltd. (JP) | 1980-02-06 | — | — | EP | disclosed |