SCHEMBL27552000

SCHEMBL27552000

CC(C)(CN=C=O)c1ccc(C(C)(C)CN=C=O)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
CYP3A4 P08684 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29270064 0.90 TAAR1 (0.47) ESR1ESR2TAAR1CYP3A4
SCHEMBL8600868 0.89 NPC1 (0.46) CYP3A4SMN1; SMN2
SCHEMBL3602247 0.86
SCHEMBL9066235 0.84 ESR1 (0.33) GABRA1GABRB2ESR1ESR2TAAR1
SCHEMBL8599213 0.80 MAPK1 (0.31) CYP3A4SMN1; SMN2
SCHEMBL6373766 0.73 MIF (0.32)
SCHEMBL11855202 0.72 CYP3A4 (0.46) GABRA1GABRB2CYP3A4
SCHEMBL5737958 0.72 NR3C1 (0.33) GABRA1GABRB2
SCHEMBL9404584 0.72 CA2 (0.45) GABRA1GABRB2
SCHEMBL11119059 0.72 CYP2C19 (0.38) ESR1ESR2TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135803-B Electroless plating base agent containing polymer and metal microparticles 日产化学株式会社 2024-06-28 CN disclosed
CN-1190502-C Hydrophobic-imparting polysiloxanes BAYER AG (DE) 2005-02-23 CN disclosed