Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | ACR | P10323 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2159024 | 0.85 | KMT2A (0.72) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27483180 | 0.85 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6652892 | 0.81 | ALDH1A1 (0.70) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27708693 | 0.80 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTHSP90AA1 | |
| SCHEMBL9479858 | 0.80 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTHSP90AA1 | |
| SCHEMBL20631546 | 0.80 | MAPT (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27527046 | 0.79 | HPGD (0.50) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27498161 | 0.79 | MAPT (0.47) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL27496498 | 0.77 | TUBB4A (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL17077807 | 0.77 | MAPT (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1188388-C | Aminobenzophenones as inhibitors of interleukin and TNF | LEO PHARM PROD LTD (DK) | 2005-02-09 | — | — | CN | disclosed |