Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 19/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2755410 | 0.92 | LTC4S (0.74) | LTC4S | |
| SCHEMBL239219 | 0.90 | LTC4S (0.71) | LTC4S | |
| SCHEMBL2755413 | 0.90 | LTC4S (0.71) | LTC4S | |
| SCHEMBL3260927 | 0.87 | LTC4S (0.77) | LTC4S | |
| SCHEMBL2755415 | 0.87 | LTC4S (0.75) | LTC4S | |
| SCHEMBL2755411 | 0.85 | LTC4S (0.74) | LTC4SKDM4EASPHKDM8 | |
| SCHEMBL2755412 | 0.85 | LTC4S (0.63) | LTC4S | |
| SCHEMBL240421 | 0.84 | LTC4S (0.74) | LTC4S | |
| SCHEMBL2755446 | 0.84 | LTC4S (1.00) | LTC4S | |
| SCHEMBL238338 | 0.84 | LTC4S (0.72) | LTC4S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | LTC4S 1/4885KDM4E 2809/4885ASPH 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.