Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367233 | 0.86 | SLC7A5 (0.64) | SLC7A5NPY1RAURKARPS6KB1NOS3 | |
| SCHEMBL3050840 | 0.86 | SLC7A5 (0.64) | SLC7A5NPY1RAURKARPS6KB1NOS3 | |
| SCHEMBL9956406 | 0.85 | ACE (0.63) | CTSLPPARGACECTSSCTSK | |
| SCHEMBL9956403 | 0.85 | ACE (0.63) | CTSLPPARGACECTSSCTSK | |
| SCHEMBL7156537 | 0.81 | MGLL (0.52) | NPY1RAURKARPS6KB1SIRT2CYP3A4 | |
| SCHEMBL999345 | 0.81 | NR1H4 (0.60) | NPY1RAURKARPS6KB1PPARGSIRT2 | |
| SCHEMBL20215005 | 0.81 | AURKA (0.47) | SLC7A5CTSLNPY1RAURKARPS6KB1 | |
| SCHEMBL20204195 | 0.81 | AURKA (0.47) | SLC7A5NPY1RAURKARPS6KB1NOS3 | |
| SCHEMBL16856591 | 0.81 | AURKA (0.47) | SLC7A5NPY1RAURKARPS6KB1NOS3 | |
| SCHEMBL8711740 | 0.81 | AURKA (0.50) | NPY1RAURKARPS6KB1PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1332964-C | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2007-08-22 | — | — | CN | disclosed |
| CN-1656107-A | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2005-08-17 | — | — | CN | disclosed |