Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794029 | 0.86 | CHRNB2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4PLAU | |
| Hydrochloric Acid SCHEMBL28665674 | 0.82 | CHRNB2 (0.50) | CHRNB2CHRNB4CHRNA3CHRNA4PLAU | |
| Buramate SCHEMBL79198 | 0.81 | PLAU (0.51) | PLAUL3MBTL1SMN1; SMN2LMNATSHR | |
| SCHEMBL19750488 | 0.81 | MAPT (0.51) | CHRNB2CHRNB4CHRNA3CHRNA4PLAU | |
| SCHEMBL28926082 | 0.80 | PLAU (0.50) | PLAUPADI3PADI4SMN1; SMN2LMNA | |
| SCHEMBL3898926 | 0.80 | PLAU (0.50) | PLAUPADI3PADI4SMN1; SMN2LMNA | |
| SCHEMBL17391736 | 0.80 | TSHR (0.54) | PLAUPADI3PADI4SMN1; SMN2LMNA | |
| SCHEMBL17346754 | 0.80 | LMNA (0.56) | PLAUPADI3PADI4MAPTSMN1; SMN2 | |
| SCHEMBL7422332 | 0.80 | HDAC1 (0.55) | PLAUL3MBTL1MAPTLMNA | |
| SCHEMBL17550887 | 0.79 | HPGD (0.53) | PLAUL3MBTL1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1301248-A | Process for preparing chiral (S)-2, 3-disubstituted-1-propylamine derivatives | SAMSUNG FINE CHEMICALS CO LTD (KR) | 2001-06-27 | — | — | CN | disclosed |