Sugi Predict

Sugi Predict / Compounds / Iscotrizinol

Iscotrizinol

Iscotrizinol

SCHEMBL275583

CCCCC(CC)COC(=O)c1ccc(Nc2nc(Nc3ccc(C(=O)NC(C)(C)C)cc3)nc(Nc3ccc(C(=O)OCC(CC)CCCC)cc3)n2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.53
▸ CYP3A4 P08684 3/20 0.53
▸ LMNA P02545 3/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ TSHR P16473 2/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ CA2 P00918 1/20 0.46
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ THRB P10828 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ PRSS1 P07477 1/20 0.42
▸ PRSS2 P07478 1/20 0.42
▸ PRSS3 P35030 1/20 0.42
▸ PDPK1 O15530 1/20 0.42
▸ JAK2 O60674 1/20 0.41
▸ JAK1 P23458 1/20 0.41
▸ TYK2 P29597 1/20 0.41
▸ JAK3 P52333 1/20 0.41
▸ ADRB2 P07550 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19823693 0.96 ALDH1A1 (0.49) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL490468 0.96 ALDH1A1 (0.49) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL19823694 0.96 ALDH1A1 (0.49) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL14986219 0.96 ALDH1A1 (0.47) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL19809122 0.95 ALDH1A1 (0.48) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL13492208 0.95 ALDH1A1 (0.48) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL12186622 0.94 ALDH1A1 (0.47) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL17576042 0.92 MEN1 (0.50) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL62195 0.91 ALDH1A1 (0.62) ALDH1A1CYP3A4LMNAHSD17B10TSHR
SCHEMBL29574971 0.89 ALDH1A1 (0.53) ALDH1A1CYP3A4LMNAHSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104705-A2 PROCESS FOR THE PRODUCTION OF C6-C18 ALKYL ESTERS OF 4-AMINOBENZOIC ACID DSM IP ASSETS B.V. (NL) 2026-05-21 — — WO claimed
WO-2026099270-A1 BIODEGRADABLE UV ABSORBERS AND USES THEREOF II BASF SE (DE) 2026-05-15 — — WO claimed
WO-2025242892-A1 SUBSTITUTED CINNAMIC ACID DERIVATIVES AS UV ABSORBERS AND USES THEREOF BASF SE (DE) 2025-11-27 — — WO claimed
WO-2025242885-A1 SUBSTITUTED CINNAMIC ACID DERIVATIVES AS UV ABSORBERS AND USES THEREOF BASF SE (DE) 2025-11-27 — — WO claimed
WO-2025242884-A1 SUBSTITUTED CINNAMIC ACID DERIVATIVES AS UV ABSORBERS AND USES THEREOF BASF SE (DE) 2025-11-27 — — WO claimed
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS TOTALENERGIES ONETECH (FR) 2025-07-10 — — US claimed
WO-2025132800-A1 PERSONAL CARE COMPOSITIONS COMPRISING LACTIC ACID ESTERS BASF SE (DE) 2025-06-26 — — WO claimed
US-20250195362-A1 COMPOSITIONS CONTAINING BIS-ETHYLHEXYLOXYPHENOL METHOXYPHENYL TRIAZINE AND AT LEAST ONE BOOSTER L'OREAL (FR) 2025-06-19 — — US claimed
EP-4547194-A1 COSMETIC FORMULATIONS COMPRISING STABLE HOMOGENEOUS AQUEOUS SUSPENSION OF BIOPOLYMERS 11584022 Canada Inc. (CA) 2025-05-07 — — EP claimed
EP-4543872-A1 MULTI-PHOTOPROTECTIVE COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-04-30 — — EP claimed
CN-113573688-A Effective sunscreen compositions with diethylamino hydroxybenzoyl hexyl benzoate, butyl methoxydibenzoyl methane and organic particulate UV filters 巴斯夫欧洲公司 2021-10-29 — — CN claimed
CN-113573690-A Effective sunscreen composition with diethylamino hydroxybenzoyl hexyl benzoate and butyl methoxy dibenzoyl methane and without octocrylene 巴斯夫欧洲公司 2021-10-29 — — CN claimed
WO-2020187767-A1 EFFICIENT SUNSCREEN COMPOSITIONS WITH DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE AND BUTYL METHOXYDIBENZOYLMETHANE FREE OF OCTOCRYLENE BASF SE (DE) 2020-09-24 — — WO claimed
WO-2020187762-A1 EFFICIENT SUNSCREEN COMPOSITIONS WITH DIETHYLAMINO HYDROXYBENZOYL HEXYL BENZOATE AND BUTYL METHOXYDIBENZOYLMETHANE BASF SE (DE) 2020-09-24 — — WO claimed
EP-1747773-B1 Photostable organic sunscreen compositions with antioxidant properties MERCK PATENT GMBH (DE) 2010-08-04 — — EP claimed
EP-1416911-B1 PERSONAL CARE COMPOSITIONS BOOTS CO PLC (GB) 2007-05-09 — — EP claimed
EP-1747773-A2 Photostable organic sunscreen compositions with antioxidant properties Merck Patent GmbH (DE) 2007-01-31 — — EP claimed
EP-1416911-A1 PERSONAL CARE COMPOSITIONS The Boots Company PLC (GB) 2004-05-12 — — EP claimed
WO-2003013468-A1 PERSONAL CARE COMPOSITIONS THE BOOTS COMPANY PLC (GB) 2003-02-20 — — WO claimed
US-6514485-B1 Combinations of sunscreens 3V SIGMA S.P.A. (IT) 2003-02-04 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250221915-A1 IMPROVEMENT OF THE WATER RESISTANCE OF COSMETIC COMPOSITIONS COMPRISING UV FILTERS C1R, CAPRIN1, CYP51A1 ALDH1A1 1512/4885CYP3A4 2171/4885LMNA 750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.