Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iscotrizinol SCHEMBL275583 | 0.96 | ALDH1A1 (0.53) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL19823693 | 0.93 | ALDH1A1 (0.49) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL19823694 | 0.93 | ALDH1A1 (0.49) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL14986219 | 0.92 | ALDH1A1 (0.47) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL19809122 | 0.92 | ALDH1A1 (0.48) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL13492208 | 0.92 | ALDH1A1 (0.48) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL15344215 | 0.91 | ALDH1A1 (0.58) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL2969474 | 0.91 | ALDH1A1 (0.58) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL12186622 | 0.90 | ALDH1A1 (0.47) | ALDH1A1LMNACYP3A4HSD17B10MAPK1 | |
| SCHEMBL17576042 | 0.88 | MEN1 (0.50) | ALDH1A1LMNACYP3A4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113573691-A | Effective sunscreen composition with diethylamino hydroxybenzoyl hexyl benzoate and butyl methoxy dibenzoyl methane | 巴斯夫欧洲公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113573690-A | Effective sunscreen composition with diethylamino hydroxybenzoyl hexyl benzoate and butyl methoxy dibenzoyl methane and without octocrylene | 巴斯夫欧洲公司 | 2021-10-29 | — | — | CN | claimed |
| EP-2259768-B1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2019-05-22 | — | — | EP | disclosed |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | MERCK PATENT GMBH (DE) | 2019-05-07 | — | — | US | disclosed |
| US-9700501-B2 | Use of indole compounds as a cosmetic | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9603784-B2 | Process for treating sol-gel capsules | MERCK PATENT GMBH (DE) | 2017-03-28 | — | — | US | disclosed |
| EP-2309974-B1 | USE OF 5-(7-METHOXY-3,3-DIMETHYL-2,3-DIHYDRO-1-BENZOXEPIN-5-YL)-3-METHYL-PENTA-2,4-DIENOIC | MERCK PATENT GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| EP-2306965-B1 | USE OF INDOLE COMPOUNDS AS A COSMETIC | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-20150265516-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-9044409-B2 | Use of chromen-4-one derivatives | MERCK PATENT GMBH (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9023889-B2 | Use of ascorbic acid derivatives for the functionalization of matrices | MERCK PATENT GMBH (DE) | 2015-05-05 | — | — | US | disclosed |
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | MERCK PATENT GMBH (DE) | 2005-01-27 | — | — | US | disclosed |
| US-20040185072-A1 | Includes 1,4,5,6-tetrahydro-4-pyrimidinecarboxylic acid derivative to enhance storage stability; self-tanning | MERCK PATENT GESELLSCHAFT (DE) | 2004-09-23 | — | — | US | disclosed |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | MERCK PATENT GMBH (DE) | 2004-05-27 | — | — | US | disclosed |
| US-20040091433-A1 | Light-protection agents | MERCK PATENT GMBH (DE) | 2004-05-13 | — | — | US | disclosed |
| US-20040081675-A1 | Cosmetic formulations containing flavonoid derivatives | MERCK PATENT GMBH (DE) | 2004-04-29 | — | — | US | disclosed |
| US-20040067894-A1 | Preparation having antioxidant properties | MERCK PATENT GMBH (DE) | 2004-04-08 | — | — | US | disclosed |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | MERCK PATENT GMBH (DE) | 2003-11-06 | — | — | US | disclosed |
| US-20030060426-A1 | Formulation for protection against oxidative stress containing benzofuranone derivatives | MERCK PATENT GMBH (DE) | 2003-03-27 | — | — | US | disclosed |
| US-20030039619-A1 | Galenic formulation | MERCK PATENT GMBH (DE) | 2003-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040091433-A1 | Light-protection agents | CBR1, CYC1, C9 | ALDH1A1 271/4885LMNA 126/4885CYP3A4 1079/4885 |
| US-20150265516-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | CUTA, NGLY1, CALCA | ALDH1A1 4788/4885LMNA 2042/4885CYP3A4 4882/4885 |
| US-20040067894-A1 | Preparation having antioxidant properties | GPX1, CBR1, CYC1 | ALDH1A1 233/4885LMNA 651/4885CYP3A4 1760/4885 |
| US-20040185072-A1 | Includes 1,4,5,6-tetrahydro-4-pyrimidinecarboxylic acid derivative to enhance storage stability; self-tanning | DHODH, DPYD, ALDH1A1 | ALDH1A1 3/4885LMNA 2839/4885CYP3A4 542/4885 |
| US-20030060426-A1 | Formulation for protection against oxidative stress containing benzofuranone derivatives | NQO1, NFE2L2, GPX4 | ALDH1A1 87/4885LMNA 824/4885CYP3A4 415/4885 |
| US-20030039619-A1 | Galenic formulation | GALR2, GALE, GLA | ALDH1A1 408/4885LMNA 169/4885CYP3A4 1320/4885 |
| US-20040102446-A1 | Tricyclic quinoxaline derivatives as a uv filter | CUTA, CYP1B1, TPH1 | ALDH1A1 289/4885LMNA 851/4885CYP3A4 116/4885 |
| US-20040081675-A1 | Cosmetic formulations containing flavonoid derivatives | TYR, MITF, TEAD3 | ALDH1A1 1603/4885LMNA 1817/4885CYP3A4 363/4885 |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | CUTA, NGLY1, CALCA | ALDH1A1 4788/4885LMNA 2042/4885CYP3A4 4882/4885 |
| US-20050019426-A1 | For care, protection from aging of skin and hair, use in treatment of various skin disorders such as leukoplakia, eczema, keratosis, psoriasis, or to promote wound healing | ITCH, CUTA, POLR1C | ALDH1A1 1876/4885LMNA 256/4885CYP3A4 4025/4885 |
| US-20030207886-A1 | Preparation containing quinoxaline derivatives | CUTA, XPA, NQO2 | ALDH1A1 1898/4885LMNA 488/4885CYP3A4 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.