Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196868 | 0.81 | HPGDS (0.51) | SIGMAR1KDM4CKDM5AKDM5BNPC1 | |
| SCHEMBL8862886 | 0.79 | HTT (0.41) | HTTHMOX1SLC6A3GSK3AGSK3B | |
| SCHEMBL21198915 | 0.79 | ADORA2A (0.44) | HTTHMOX1SLC6A3SIGMAR1ADORA2A | |
| SCHEMBL28800303 | 0.79 | QPCT (0.44) | HTTHMOX1CNOT7POLBKMT2A | |
| SCHEMBL28802435 | 0.77 | HPGDS (0.55) | HTTHMOX1KDM4CKDM5AKDM5B | |
| SCHEMBL15473178 | 0.76 | HTT (0.41) | HTTHMOX1SLC6A3KDM4CMAPT | |
| SCHEMBL6496954 | 0.75 | HTT (0.41) | HTTHMOX1SLC6A3GSK3AGSK3B | |
| SCHEMBL4185102 | 0.72 | HTT (0.47) | HTTHMOX1SLC6A3GSK3AGSK3B | |
| SCHEMBL1395967 | 0.72 | TAAR1 (0.63) | SIGMAR1KMT2A | |
| Hydrochloric Acid SCHEMBL19468892 | 0.71 | TAAR1 (0.62) | SIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1330661-A | Procollagen C-proteinase inhibitors | HOFFMANN LA ROCHE (CH) | 2002-01-09 | — | — | CN | disclosed |