Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273726 | 0.84 | — | — | |
| SCHEMBL1050966 | 0.78 | ALDH1A1 (0.39) | DPP4SMN1; SMN2USP2ALDH1A1LMNA | |
| SCHEMBL10505523 | 0.77 | DPP4 (0.43) | DPP4KEAP1SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL27093605 | 0.77 | DPP4 (0.43) | DPP4KEAP1SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL4676100 | 0.77 | DPP7 (0.33) | — | |
| SCHEMBL11883477 | 0.76 | USP2 (0.52) | KEAP1SMN1; SMN2USP2ALDH1A1LMNA | |
| SCHEMBL3720186 | 0.75 | DPP4 (0.42) | DPP4KEAP1SMN1; SMN2USP2ALDH1A1 | |
| SCHEMBL231163 | 0.75 | KMT2A (0.37) | SMN1; SMN2USP2ALDH1A1LMNAMAPT | |
| SCHEMBL27586544 | 0.75 | ALDH1A1 (0.39) | USP2ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL4805804 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1346272-A | Cystine derivatives as therapeutic agents for matrix metalloprotease related diseases | ROCHE DIGNOSTICS GMBH (DE) | 2002-04-24 | — | — | CN | disclosed |