Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PHGDH | O43175 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6123340 | 0.78 | ANPEP (0.34) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL181625 | 0.78 | ALDH1A1 (0.39) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL6505658 | 0.78 | ANPEP (0.38) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL10505523 | 0.77 | DPP4 (0.43) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL27093605 | 0.77 | DPP4 (0.43) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL27558609 | 0.75 | DPP4 (0.42) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL8557598 | 0.75 | KMT2A (0.37) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL7539239 | 0.74 | DPP7 (0.48) | ANPEP | |
| SCHEMBL2485265 | 0.73 | KMT2A (0.41) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 | |
| SCHEMBL39810 | 0.73 | KMT2A (0.41) | DPP4KEAP1SMN1; SMN2ANPEPUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128345-A1 | KYNURENIC ACID ANALOGUES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USE OF SAID COMPOUNDS FOR THE TREATMENT OF HEADACHE | Szegedi Tudományegyetem (HU) | 2010-11-11 | — | — | WO | disclosed |