Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | YWHAG | P61981 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034170 | 0.84 | CYP1A2 (0.53) | MAOALMNAKDM4ENPC1TP53 | |
| SCHEMBL4668894 | 0.83 | ALDH1A1 (0.45) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL14070437 | 0.83 | CYP1A2 (0.45) | MAOALMNAKDM4ENPC1TP53 | |
| Hydrochloric Acid SCHEMBL27558956 | 0.83 | CYP1A2 (0.51) | MAOALMNAKDM4ENPC1TP53 | |
| SCHEMBL6233836 | 0.83 | SMN1; SMN2 (0.45) | MAOALMNAKDM4ENPC1TP53 | |
| SCHEMBL14852200 | 0.81 | MAOB (0.49) | MAOAALDH1A1MAOB | |
| SCHEMBL13422217 | 0.79 | PPARA (0.48) | ALDH1A1 | |
| SCHEMBL5776297 | 0.78 | CYP1A2 (0.41) | MAOALMNAKDM4ENPC1TP53 | |
| SCHEMBL26813604 | 0.78 | KDM4E (0.49) | LMNAKDM4ENPC1MAPTRAB9A | |
| SCHEMBL5778334 | 0.78 | CYP1A2 (0.41) | MAOALMNAKDM4ENPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1359373-A | 6- [ [ (aryl and heteroaryl) oxy ] methyl ] -naphthyl-2-carboximidamide derivatives, process for their preparation and their use in therapy | SANOFI SYNTHELABO (FR) | 2002-07-17 | — | — | CN | disclosed |