Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610342 | 0.85 | AKR1B1 (0.54) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL5462218 | 0.84 | AKR1B1 (0.70) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL9162776 | 0.77 | MEN1 (0.54) | AKR1B1MEN1KMT2AMAPTCYP19A1 | |
| SCHEMBL27558978 | 0.76 | AKR1B1 (0.68) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL27558983 | 0.76 | AKR1B1 (0.54) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL5470857 | 0.76 | AKR1B1 (0.66) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL5483642 | 0.72 | AKR1B1 (0.52) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL11821210 | 0.72 | MEN1 (0.47) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL1130974 | 0.70 | KMT2A (0.58) | POLBMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL29469269 | 0.70 | KMT2A (0.58) | POLBMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1364153-A | Substituted phenoxyacetic acids | INST PHARMACEUTICAL DISCOVERY (US) | 2002-08-14 | — | — | CN | disclosed |