Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462218 | 0.86 | AKR1B1 (0.70) | AKR1B1PTPN7DUSP3POLBMEN1 | |
| SCHEMBL27558982 | 0.85 | AKR1B1 (0.54) | AKR1B1PTPN7DUSP3POLBMEN1 | |
| SCHEMBL5470857 | 0.77 | AKR1B1 (0.66) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL5483642 | 0.76 | AKR1B1 (0.52) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL8889014 | 0.72 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1MAOA | |
| SCHEMBL5457602 | 0.72 | AKR1B1 (0.75) | AKR1B1PTPN7DUSP3MEN1KMT2A | |
| SCHEMBL3442245 | 0.71 | PTPN1 (0.57) | AKR1B1POLBMEN1KMT2AMAPT | |
| SCHEMBL11821210 | 0.70 | MEN1 (0.47) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL5465148 | 0.70 | AKR1B1 (1.00) | AKR1B1PTPN7DUSP3MEN1KMT2A | |
| SCHEMBL30791550 | 0.69 | PTPN1 (0.61) | POLBMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1198451-A2 | SUBSTITUTED PHENOXYACETIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001000566-A2 | SUBSTITUTED PHENOXYACETIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-01-04 | — | — | WO | disclosed |