Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27585477 | 0.79 | HTR2B (0.40) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL304034 | 0.70 | ALDH1A1 (0.41) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL28774780 | 0.68 | AR (0.42) | ARMEN1KMT2AFDPS | |
| SCHEMBL7112576 | 0.66 | L3MBTL1 (0.55) | ALDH1A1 | |
| SCHEMBL29373097 | 0.65 | CYP3A4 (0.53) | ARMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL36019 | 0.65 | CYP3A4 (0.53) | ARMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL28132393 | 0.65 | CYP2D6 (0.44) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL29956572 | 0.65 | — | — | |
| SCHEMBL27928110 | 0.65 | — | — | |
| SCHEMBL31713019 | 0.64 | ALDH1A1 (0.35) | ARMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1309647-A | Substd. 6-benzyl-4-oxopyrimidines, process for their preparation and pharmaceutical compositions contg. them | NOVIRIO PHARMACEUTICALS LTD (KY) | 2001-08-22 | — | — | CN | disclosed |