SCHEMBL27562005

SCHEMBL27562005

CCOC(=O)c1ccc(C(=O)OO)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.53
CA1 P00915 4/20 0.53
CA2 P00918 4/20 0.53
CA7 P43166 4/20 0.53
CA9 Q16790 4/20 0.53
CA14 Q9ULX7 4/20 0.53
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
HSD17B2 P37059 1/20 0.48
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
MAOA P21397 1/20 0.47
TSHR P16473 2/20 0.47
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
CASP3 P42574 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31070226 1.00 CA12 (0.53) CA12CA1CA2CA7CA9
SCHEMBL8669772 0.92 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL2292998 0.90 CA12 (0.59) CA12CA1CA2CA7CA9
SCHEMBL9008367 0.85 TSHR (0.56) CA12CA1CA2CA7CA9
SCHEMBL9450650 0.85 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL27476698 0.84 TSHR (0.51) CA12CA1CA2CA7CA9
Water SCHEMBL27703024 0.84 TSHR (0.55) CA12CA1CA2CA7CA9
SCHEMBL29843135 0.83 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL321387 0.83 CA12 (0.62) CA12CA1CA2CA7CA9
SCHEMBL1401558 0.83 CA12 (0.54) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1349571-A Tow and process of making same DU PONT (US) 2002-05-15 CN disclosed